From San Diego take the 15 Freeway (North) to the Clinton Keith Road (West) off-ramp near Murrieta.

When leaving the 15 Freeway West on Clinton Keith, drive to the point where you come to a stop sign, turn right on Tenaja Road. Follow Tenaja Road through the Nature Conservancy and in a few miles you'll see the Buffalo Ranch at the corner of Tenaja Road and Calle Bandido. You've then arrived at the Home of the Famous - "Buffalo Run."